Reagent kit for the determination of immunoglobulins of classes M (IgM) and / or G (IgG) to the SARS-CoV-2 coronavirus causing COVID-19
A set of reagents for the determination of immunoglobulins of classes M (IgM) and / or G (IgG) to the SARS-CoV-2 coronavirus causing COVID-19 The test is intended for the simultaneous detection of immunoglobulins M (IgM) and G (IgG) to the SARS-CoV-2 coronavirus in serum (plasma) of human blood by the method of solid-phase indirect enzyme-linked immunosorbent assay (ELISA)
Application of the "SARS-CoV-2 IgM / IgG Screen" reagent kit
The set of reagents "SARS-CoV-2 IgM / IgG Screen" (diagnosis of COVID-19) is significantly cheaper than molecular tests and can be used for large-scale studies to determine the true lethality and dynamics of the spread of SARS-CoV-2, which will contain the spread of the pathogen COVID -19 after the termination of quarantine measures.
Kits for the determination of antibodies to the SARS-CoV-2 virus
Initially, the fact of infection with SARS-CoV-2 was confirmed by the identification of the RNA of the pathogen. Now these tests are widely used and are represented by sets of both foreign and domestic production. Test systems of the PCR-Rt and LAMP format (loop isothermal amplification) are mainly used. But, unfortunately, molecular research methods, despite their high analytical characteristics, have a number of disadvantages.
First, the sensitivity and specificity of molecular methods in practice are often lower than the test manufacturers claim. This is due to the significant influence on the reliability of the study of the method, place and time of taking the material, the qualifications of personnel.
Secondly, the amount of RNA of the pathogen in the sample may be less than the sensitivity threshold of the test.
Thirdly, molecular methods are quite expensive, in most cases they require special equipment and trained personnel. This significantly limits the possibilities of their mass use.
Fourthly, molecular methods cannot be used to identify those who have already had COVID-19 in order to fully analyze the epidemic process.
adjuvant for the diagnosis of COVID-19 in patients with acute respiratory syndrome
identification of asymptomatic and erased forms of COVID-19 in the foci of the disease, examination of those in contact with those infected with the SARS-CoV-2 virus
examination of persons arriving from regions with a high level of COVID-19 disease and their re-examination before leaving the observation
identification of COVID-19 patients, regardless of the form of the infectious process
Antibodies to SARS-CoV-2 begin to be detected 1-2 weeks after the onset of clinical symptoms, reaching a maximum at 3-4 weeks. Then the IgM level gradually decreases, until it disappears completely. IgG levels are maintained, providing a sustained immune response.
Pros of enzyme immunoassay
Interpretation of results
High stability of reagents
Unique specificity of the immunochemical reaction in ELISA, i.e. antibodies bind exclusively to specific antigens, and not to any other
Simplicity of registration methods
Widespread use of monoclonal antibodies
Promptly obtained results
IgM / IgG Screen".
ELISA "SARS-CoV-2 IgG Screen".
ELISA "SARS-CoV-2 IgM Screen"
A set of reagents for the simultaneous determination of immunoglobulin classes M (IgM) + G (IgG) to the SARS-CoV-2 coronavirus, which causes COVID-19.
A set of reagents for the simultaneous determination of immunoglobulins of classes G (IgG) to the SARS-CoV-2 coronavirus, which causes COVID-19.
A set of reagents for the simultaneous determination of immunoglobulins of classes M (IgM) to the SARS-CoV-2 coronavirus, which causes COVID-19.
Properties and characteristics
Determination of IgG titers
Detection of IgM by capture method
Simultaneous determination of IgM / IgG
Ready-to-use controls, conjugate and chromogen solutions
Analysis of 96 samples, including control ones. fractional use of sets is possible
Samples - serum or blood plasma
Storage of all kit components is carried out at a temperature of 2-8 °С
Possibility of transportation at temperatures from 9 ° to 28 ° С no more than 7 days
Total analysis time 1 hour 25 minutes